Introduction Aspartyl/asparaginyl beta-hydroxylase (HAAH) is an essential enzyme in the human body, encoded by the ASPH gene located on chromosome 8. This enzyme belongs to a broader family of alpha-ketoglutarate-dependent hydroxylases, which are characterized by their non-haem iron-containing proteins. The significance of HAAH extends beyond its basic biochemical role, as it has been implicated in…